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于博芮 減重可治療體重過重婦女的尿失禁問題 2009/3/18 上午 09:10:10 0
原 文 題  目 Weight Loss to Treat Urinary Incontinence in Overweight and Obese Women
作  者 Leslee L. Subak
出  處 The new england journal o f medicine, 360;5, p481-490
出版日期 january 29, 2009
評 論 由於營養攝取的不均衡,現代人易出現肥胖問題,而肥胖也是導致代謝症候群的原因之ㄧ。肥胖者也易出現尿失禁的問題,然而減重後是否會緩解尿失禁的現象?缺乏實證資料,本研究以隨機分派個案至控制組與實驗組中,兩組皆提供自我學習骨盆底肌訓練手冊,實驗組進行減重活動。六個月後減重組尿失禁次數減少且達統計差異,不過本研究未對骨盆底肌訓練的影響多討論,減重與骨盆底肌訓練對於肥胖者失禁緩解何者較重要?或許是未來研究探討重點。
abstract Background
Obesity is an established and modifiable risk factor for urinary incontinence, but
conclusive evidence for a beneficial effect of weight loss on urinary incontinence is
lacking.
Methods
We randomly assigned 338 overweight and obese women with at least 10 urinaryincontinence
episodes per week to an intensive 6-month weight-loss program that
included diet, exercise, and behavior modification (226 patients) or to a structured
education program (112 patients).
Results
The mean (±SD) age of the participants was 53±11 years. The body-mass index
(BMI) (the weight in kilograms divided by the square of the height in meters) and
the weekly number of incontinence episodes as recorded in a 7-day diary of voiding
were similar in the intervention group and the control group at baseline (BMI, 36±6
and 36±5, respectively; incontinence episodes, 24±18 and 24±16, respectively). The
women in the intervention group had a mean weight loss of 8.0% (7.8 kg), as compared
with 1.6% (1.5 kg) in the control group (P<0.001). After 6 months, the mean
weekly number of incontinence episodes decreased by 47% in the intervention group,
as compared with 28% in the control group (P = 0.01). As compared with the control
group, the intervention group had a greater decrease in the frequency of stressincontinence
episodes (P = 0.02), but not of urge-incontinence episodes (P = 0.14).
A higher proportion of the intervention group than of the control group had a clinically
relevant reduction of 70% or more in the frequency of all incontinence episodes
(P<0.001), stress-incontinence episodes (P = 0.009), and urge-incontinence episodes
(P = 0.04).
Conclusions
A 6-month behavioral intervention targeting weight loss reduced the frequency of
self-reported urinary-incontinence episodes among overweight and obese women
as compared with a control group. A decrease in urinary incontinence may be another
benefit among the extensive health improvements associated with moderate
weight reduction.
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