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張尚仁 肥胖程度和膀胱過動症的關聯性受性別影響:波士頓社區健康調查 2011/2/20 下午 06:24:15 0
原 文 題  目 The Association of Adiposity and Overactive Bladder Appears to Differ by Gender: Results From the Boston Area Community Health Survey
作  者 Carol L. Link, William D. Steers John W. Kusek and John B. McKinlay
出  處 Journal of Urology
出版日期 Vol. 185, 955-963, March 2011
評 論 肥胖程度和膀胱過動症狀的關聯性受性別影響。
Conclusions: The relationship between adiposity and overactive bladder varies by gender.
abstract 研究目的:本篇文章探討肥胖程度(腰圍、臀圍、腰臀比和BMI)與膀胱過動症(頻尿和急尿)的關聯性是否受性別和年齡的影響。

材料和方法:波士頓地區社區健康調查研究5503居民,年齡介於30歲到79歲之間,來自三個種族。

結果:此研究發現性別會影響肥胖程度和膀胱過動症的關聯性。在男女雙方,腰臀比都不會顯著影響膀胱過動症狀。但女性腰圍、臀圍或BMI較高者,其膀胱過動症狀也較明顯。在男性則不同,腰圍100公分以下、臀圍115公分以下、BMI 27.5以下,膀胱過動症狀和肥胖度呈反比,超過此數值,膀胱過動症狀則和肥胖度呈正相關。


Purpose: We investigate the association of different measures of adiposity (waist circumference, hip circumference, waist-to-hip ratio and body mass index) with overactive bladder (urinary frequency and urgency), whether the association varies by gender or age and whether it persists when models are adjusted for other confounders.


Materials and Methods: Data were from the Boston Area Community Health epidemiological survey, a random sample of 5,503 Boston, Massachusetts, residents 30 to 79 years old with equal representation from 3 racial/ethnic groups (black, Hispanic and white). Statistical analysis involved nonparametric loess models and multivariate logistic regression.


Results: We noted distinct patterns by gender for the association of various adiposity measures with overactive bladder. Waist-to-hip ratio was not significantly associated with overactive bladder in either gender. In women the prevalence of overactive bladder increased as waist (OR adjusted for other confounders 1.10/10 cm increase) or hip circumference (OR 1.12/10 cm increase) or body mass index (OR 1.03/kg/m2 increase) increased. In men the prevalence of overactive bladder decreased as adiposity increased (OR 0.65/10 cm increase in waist circumference, OR 0.71/10 cm increase in hip circumference and OR 0.87/kg/m2 in body mass index) but only to a certain point (waist circumference 100 cm, hip circumference 115 cm and body mass index 27.5 kg/m2, respectively). At that point the prevalence of overactive bladder increased with increasing adiposity (OR 1.19/10 cm increase in waist circumference, OR 1.16/10 cm increase in hip circumference and OR 1.08/kg/m2 in body mass index).
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