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| 發表人 | 討論主題 | 發表時間 | 討論數 |
| 蒙恩醫師 | 生活方式因子，良性攝護腺增生及下泌尿道症狀 | 2011/3/22 下午 05:47:55 | 0 |
| 原 文 | 題 目 | Lifestyle factors, benign prostatic hyperplasia, and lower urinary tract symptoms |
| 作 者 | Parsons, J. K. | |
| 出 處 | Curr Opin Urol 2011: 21, 1-4. | |
| 出版日期 | Jan, 2011 | |
| 評 論 | 雖然年齡，遺傳和性激素被認為是造成良性前列腺增生症（BPH）和下尿路症狀（LUTS）的主要因素，最近的流行病學研究發現，生活方式的改變也與此病況的產生息息相關。生活方式與代謝因素顯著增加良性前列腺增生及下尿路症狀的風險，包括肥胖、糖尿病及食用肉類和脂肪。降低這種風險的相關因素包括運動，適度飲酒，和多吃蔬菜。血脂和吸煙是否為危險因子則目前還不清楚。生活方式改變，如減重，運動和飲食習慣改變（少攝取油脂，多攝取蔬果），是否能有效預防或治療良性前列腺增生及下尿路症狀，目前也還有待大型的隨機臨床試驗提供更多的證據。生活方式因子為預防和治療良性前列腺增生及下尿路症狀開創了新的視野。雖然改變生活方式的臨床試驗尚未展開，但是推廣的健康生活方式對於治療良性前列腺增生症和下尿路症狀絕對是有潛在好處的。 | |
| abstract |
PURPOSE OF REVIEW: Although age, genetics, and sex steroid hormones play prominent roles in the cause of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS), recent epidemiological studies suggest that modifiable lifestyle factors also contribute substantially to the pathogenesis of these conditions. RECENT FINDINGS: Lifestyle and metabolic factors associated with significantly increased risks of benign prostatic hyperplasia and lower urinary tract symptoms include obesity, diabetes, and meat and fat consumption. Factors associated with decreased risks include physical activity, moderate alcohol intake, and vegetable consumption. Factors for which no clear risk patterns have emerged include lipids and smoking. Randomized clinical trials of lifestyle alterations - such as weight loss, exercise, and diet - for the prevention or treatment of benign prostatic hyperplasia and lower urinary tract symptoms have yet to be performed. SUMMARY: Lifestyle factors present a novel opportunity for the prevention and treatment of benign prostatic hyperplasia and lower urinary tract symptoms. Although clinical trials of lifestyle modifications have not yet been undertaken, promotion of healthy lifestyle alternatives within the context of standard benign prostatic hyperplasia and lower urinary tract symptoms treatment algorithms is potentially beneficial. |
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