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| 發表人 | 討論主題 | 發表時間 | 討論數 |
| 蒙恩 | 下泌尿道症狀的嚴重度與睡眠障礙的關係 | 2011/9/28 下午 02:15:25 | 0 |
| 原 文 | 題 目 | The Relationship Between Lower Urinary Tract Symptom Severity and Sleep Disturbance in the CAMUS Trial |
| 作 者 | Bruschini H, Simonetti R, Antunes AA, Srougi M. | |
| 出 處 | J. Urol. 2011:185(6), 2223-8 | |
| 出版日期 | Jun, 2011 | |
| 評 論 | 就像是睡眠障礙一樣，惱人的下尿路症狀，包括夜尿，明顯地影響了男性的整體健康及相關的生活品質。然而，很少有人真正研究下尿路症狀嚴重程度與睡眠障礙之間的關係。此篇作者使用美國泌尿科醫學會的症狀指數、生活品質滿意度量表及睡眠障礙評分表來評估參與植物療法臨床研究計畫的一群男性。共有366位平均年齡60.9歲的男性參與此項試驗，他們都有中到重度的下尿路症狀（美國泌尿科醫學會的症狀指數為14.58 ± 4.6分）及平均Jenkins 睡眠障礙評分為7.3 ± 4.7分。整體來說，下尿路症狀指數與睡眠障礙嚴重程度之間有顯著的關係。多變量分析發現，阻塞性和刺激性症狀明顯伴有嚴重的睡眠障礙。進一步分析顯示，有著嚴重下尿路症狀的男性，若是其有較低的血清前列腺特異抗原(PSA)和殘餘尿量較容易產生睡眠障礙。下尿路症狀的嚴重程度是男性嚴重睡眠障礙的一危險因素。雖然夜尿與睡眠障礙有非常顯著的關連性，其他下尿路症狀也可用來作為預測睡眠障礙的因子。 | |
| abstract |
Purpose : Bothersome lower urinary tract symptoms, including nocturia, significantly impact general health related quality of life in men, as does sleep disturbance. However, few groups have examined the relationship between urinary symptom severity and sleep disturbance. Materials and Methods : Men enrolled in a clinical trial of saw palmetto (Serenoa repens) were studied at baseline. Lower urinary tract symptom severity, as determined by the American Urological Association symptom index and quality of life scores, and the degree of sleep disturbance were determined by the Jenkins sleep scale. Analysis was done, adjusting for baseline characteristics, to identify predictors of severe sleep disturbance. Results : A total of 366 men with a mean ± SD age of 60.9 ± 8.3 years who had moderate-severe lower urinary tract symptoms (mean American Urological Association symptom index score 14.58 ± 4.6 points) and a mean Jenkins sleep score of 7.3 ± 4.7 points were included in analysis. Overall there were significant associations between the American Urological Association symptom index score and sleep disturbance severity. Multivariate analysis revealed that obstructive and irritative symptoms were significantly associated with severe sleep disturbance. Further analysis showed that lower serum prostate specific antigen and post-void residual urine volume were also significantly associated with the degree of sleep disturbance. Conclusions : Lower urinary tract symptom severity is a risk factor for severe sleep disturbance in men. While nocturia was significantly associated with sleep disturbance, other lower |
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