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| 發表人 | 討論主題 | 發表時間 | 討論數 |
| 李偉嘉 | 嚴重等級的慢性心臟衰竭增加膀胱過動症與下泌尿道症狀風險 | 2012/1/30 上午 10:49:36 | 0 |
| 原 文 | 題 目 | High classification of chronic heart failure increases risk of overactive bladder syndrome and lower urinary tract symptoms. |
| 作 者 | Chiu AF, Liao CH, Wang CC, Wang JH, Tsai CH, Kuo HC. | |
| 出 處 | Urology | |
| 出版日期 | 2011 Nov 30, Epub | |
| 評 論 | 慢性心衰竭與下泌尿道症狀的關係，也是筆者懸壺期間ㄧ直思考的問題之ㄧ。在此篇論文之中，作者們指出慢性心臟衰竭患者，比起對照組有較高的貯存性症狀與膀胱過動評分，同時慢性心衰竭指數較高的病患，有較高的膀胱過動症指數。這些症狀的產生在統計中顯示與利尿劑的使用無關，而與BMI增加或肺部疾病有關。這些結果有助於大家重新思考膀胱過動症的問題，在全人醫療的觀點之下，全身健康的程度與一些慢性疾病，如糖尿病、紅斑性狼瘡、甲狀腺功能異常等常會造成下泌尿道症狀的產生。膀胱過動症的產生常常不只源自於膀胱本身的異常，而可能受到各個器官間互相干擾的影響，尤其能影響全身的疾病都是可能的風險因素。在此，又恭喜郭理事長的研究團隊為台灣學術界發光發熱。 | |
| abstract |
OBJECTIVE: To assess the urologic symptoms among patients with chronic heart failure (CHF) and to explore whether a higher classification of CHF increases the risk associated with overactive bladder syndrome (OAB) and lower urinary tract symptoms. METHODS: A total of 214 ambulatory patients with CHF (129 men and 85 women) and 378 age-matched subjects (222 men and 156 women) were enrolled in the present study. The urologic symptoms were evaluated using the Overactive Bladder Symptom Score (OABSS) and International Prostate Symptom Score (IPSS) from January to June 2010. RESULTS: Compared with the controls, the patients with CHF had a significantly greater mean OABSS (4.6 ± 3.6 vs 3.4 ± 3.1, P < .001), total IPSS (8.3 ± 6.9 vs 6.9 ± 7.6, P = .021), and storage IPSS (4.8 ± 3.5 vs 3.7 ± 3.3, P < .001). Of the patients with CHF, 34.1% had moderate/severe OAB symptoms (OABSS ≥6), and 43.5% had moderate/severe lower urinary tract symptoms (IPSS ≥8). Compared with patients who had New York Heart Association (NYHA) class I CHF, the patients with NYHA class III CHF had a significantly greater OABSS and total, storage, and voiding IPSSs. Patients with NYHA class II CHF did not. A greater body mass index and stroke were significantly associated with the OABSS and storage IPSS, and pulmonary disease was significantly associated with the voiding IPSS. CONCLUSION: The patients with CHF had more storage urinary symptoms suggestive of OAB than did the age-matched controls. Among the patients with CHF, greater NYHA class heart function was significantly associated with OAB and lower urinary tract symptoms. |
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