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| 發表人 | 討論主題 | 發表時間 | 討論數 |
| 蒙恩 | 針對有夜尿症狀之良性攝護腺阻塞病人的睡眠分析 | 2013/2/26 上午 10:51:12 | 0 |
| 原 文 | 題 目 | Sleep Analysis of Patients With Nocturia and Benign Prostatic Obstruction |
| 作 者 | Kaan Bal, Sibel Ayik, Yasar Issi, Ahmet Bolukbasi, and Galip Akhan | |
| 出 處 | UROLOGY 80: 383–388, 2012 | |
| 出版日期 | 2012 | |
| 評 論 | 本篇文章主要針對良性前列腺阻塞患者使用多導睡眠圖（PSG）分析夜尿次數及時間對睡眠品質的影響。從2009年8月至2010年8月，有20例確診為良性前列腺阻塞患者。以PSG實施睡眠評估，並使用愛普渥斯嗜睡度量表(The Epworth Sleepiness Scale)評估患者的嗜睡狀況。由來自多導睡眠圖的睡眠記錄圖，計算睡眠效率，睡眠總時間，和快速眼球運動睡眠時間，進而評估夜尿對睡眠品質的影響。結果在的平均年齡為60.48.59歲（範圍44-74），國際前列腺症狀評分為19.3 4.9，國際前列腺症狀評分中的夜尿分數為3.5 1.05（範圍2-5），PSG記錄到的夜尿次數為1.351.2次（範圍0-4）。 有6例患者（30％），愛普渥斯嗜睡度量表評分為病理狀態（>8分）。夜尿與白天嗜睡增加呈正相關，但它與睡眠效率或總睡眠時間並沒有相關。這些參數會受睡眠呼吸暫停低通氣指數（apnea-hypopnea index; 阻塞性睡眠呼吸暫停的主要指標）影響。 20例患者中，14（70％）在PSG中出現夜尿，在這些患者中，作者分別錄得23次夜尿發生，多發生在淺睡眠階段（16/ 23=[70％]）。只有7次夜尿（30％）是發生在深睡階段。深睡眠夜尿症患者的與淺表性睡眠夜尿症患者的睡眠品質沒有顯著的差異。這研究結果顯示，夜尿症主要發生在淺睡或快速眼動階段，並與良性前列腺阻塞患者的白天嗜睡增加有關。夜尿發生的時間和頻率並不會顯著影響睡眠品質;然而，若是有阻塞性睡眠呼吸中止則會對這些參數有負向影響。由此篇文章看來，有良性前列腺阻塞的患者，對其夜尿症狀應該積極治療，以免影響其白天的工作與生活。 | |
| abstract |
Objective. To analyze the timing of nocturia during sleep and its effect on sleep quality using the polysomnography (PSG) findings from patients with benign prostatic obstruction. Materials and Methods From August 2009 to August 2010, 20 patients diagnosed with benign prostatic obstruction were enrolled in the present study. The sleep evaluation was performed by PSG. The Epworth index was used to evaluate the sleepiness of the patients. The effect of nocturia on sleep quality is evaluated by sleep efficacy, total sleep time, and rapid eye movement sleep duration, calculated from the hypnograms derived from the polysomnograms. Results The mean age, total International Prostate Symptom Score, nocturia frequency on International Prostate Symptom Score, and frequency of nocturia recorded during PSG was 60.48.5 years (range 44-74), 19.3 4.9 (range 10-28), 3.5 1.05 (range 2-5), and 1.351.2 (range 0-4), respectively. In 6 patients (30%), the Epworth sleepiness score was pathologic (score >8). Nocturia correlated positively with increased daytime sleepiness, however it did not correlate with sleep efficacy or total sleep time. These parameters were affected by the apnea-hypopnea index, the major determinant of obstructive sleep apnea. Of the 20 patients, 14 (70%) experienced nocturia during PSG, and in these patients, we recorded 23 nocturia episodes that mostly occurred in the superficial sleep stage (16 [70%] of 23). Only 7 nocturia episodes (30%) occurred in the deep sleep stage. The sleep quality of patients with deep sleep nocturia did not differ from that of patients with superficial sleep nocturia. Conclusions The results of our study have shown that nocturia predominantly occurs during the superficial sleep or rapid eye movement stage and is related to increased daytime sleepiness in patients with benign prostatic obstruction. The timing and frequency of nocturia had no significant affect on sleep quality; however, the presence of obstructive sleep apnea negatively interfered with these parameters. |
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