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李建達 膀胱疼痛症候群/間質性膀胱炎之婦女患有性功能障礙的盛行率及其關聯性 2013/3/27 上午 11:54:19 0
原 文 題  目 Prevalence and correlates of sexual dysfunction among women with bladder pain syndrome/interstitial cystitis.
作  者 Bogart LM, Suttorp MJ, Elliott MN, Clemens JQ, Berry SH.
出  處 Urology. 2011 Mar;77(3):576-80. doi: 10.1016/j.urology.2010.10.016.
出版日期 Mar, 2011.
評 論 目的:在RAND間質性膀胱炎流行病學的研究,藉由使用機率抽樣來調查一般美國家庭膀胱疼痛症候群/間質性膀胱炎(BPS/IC)造成之婦女的性功能障礙之盛行率與其關聯。性功能障礙會導致患有BPS/IC的婦女其生活品質變差。

方法:電訪146,231個家庭,以確認患有膀胱症狀或BPS/IC診斷之婦女。這些女性會使用RAND間質性膀胱炎的流行病學研究高特異性症狀標準以進行第二階段的篩選。這些標準包含骨盆腔疼痛、壓力或不適;白天小便頻率≥10次或因為疼痛,壓力或不安(不是怕尿床)而尿急;膀胱脹滿而加劇的痛;經抗生素治療後,膀胱症狀沒有解決;及患者從未注射激素治療子宮內膜異位症。符合RAND間質性膀胱炎的的流行病學標準的婦女(N =1469),被完善地評估BPS/IC依存性及一般的性功能障礙、膀胱症狀的嚴重程度、一般身體健康、憂鬱症,求醫行為和社會人口學特徵。

結果:在過去4週的,與目前的性夥伴(75%),一般的性功能障礙症狀有88%,BPS/ IC相關性功能障礙症狀有90%。在多變量模式中,BPS / IC相關的性功能障礙跟更嚴重的BPS / IC症狀、年輕、憂鬱症惡化以及較差的自覺健康狀態有顯著地相關。一般性功能障礙的多變量相關因子包括非拉丁美洲人、已婚及有憂鬱症。

結論:本文研究結果顯示,患有BPS / IC的婦女有更高比例的性功能障礙。並且,性功能障礙程度與其症狀有關。然而,我們的病人大多不去討論、3/4病人更不會自動地尋求醫療協助。本文提醒身為醫療人員的我們,要適時地結合泌尿科、婦產科、精神科、物理治療師、性治療及諮詢師等專家團隊,給予幫助及治療。
abstract
OBJECTIVES: To examine the prevalence and correlates of general and bladder pain syndrome/interstitial cystitis (BPS/IC)-specific sexual dysfunction among women in the RAND Interstitial Cystitis Epidemiology study using a probability sample survey of U.S. households. Sexual dysfunction can contribute to a reduced quality of life for women with bladder pain syndrome/interstitial cystitis (BPS/IC).

METHODS: We telephoned 146,231 households to identify women who reported bladder symptoms or a BPS/IC diagnosis. Those who reported either underwent a second-stage screening using the RAND Interstitial Cystitis Epidemiology study high-specificity symptom criteria. The criteria were pain, pressure, or discomfort in pelvic area; daytime urinary frequency ≥10 times or urgency due to pain, pressure, or discomfort (not fear of wetting); pain that worsened as the bladder filled; bladder symptoms did not resolve after antibiotic treatment; and patients never treated with hormone injections for endometriosis. Women who met the RAND Interstitial Cystitis Epidemiology criteria (n = 1469) completed measures of BPS/IC-specific and general sexual dysfunction symptoms, bladder symptom severity, general physical health, depression, medical care-seeking, and sociodemographic characteristics.

RESULTS: Of those with a current sexual partner (75%), 88% reported ≥1 general sexual dysfunction symptom and 90% reported ≥1 BPS/IC-specific sexual dysfunction symptom in the past 4 weeks. In the multivariate models, BPS/IC-specific sexual dysfunction was significantly associated with more severe BPS/IC symptoms, younger age, worse depression symptoms, and worse perceived general health. Multivariate correlates of general sexual dysfunction included non-Latino race/ethnicity, being married, and having depression symptoms.

CONCLUSIONS: The results of our study have shown that women with BPS/IC symptoms experience very high levels of sexual dysfunction. Also, sexual dysfunction covaries with symptoms.
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