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蘇世桓 骨盆肌肉訓練在根除性攝護腺切除手術針對尿失禁的影響 2023/5/12 上午 11:05:27 0
原 文 題  目 Pelvic floor muscle training in radical prostatectomy: a randomized controlled trial of the impacts on pelvic floor muscle function and urinary incontinence
作  者 Joanne E. Milios, Timothy R. Ackland and Daniel J. Green
出  處 BMC Urology (2019) 19:116
出版日期 November 15, 2019
評 論 攝護腺癌症男性中相當常見的的一種癌症,目前根除性攝護腺切除已幾乎成為局部性攝護腺癌常見的手術方式,而攝護腺切除術後所導致的尿失禁是一個相對複雜且會造成病人生活極大困擾的一疾病,針對此類型的疾病大部分的治療包括骨盆肌肉訓練(pelvic floor muscle training),生理回饋治療(bio-feedback),甚至是手術治療。此篇研究發展新的一種骨盆肌肉訓練其中包含了活動慢肌及快肌,並強調在術前就開始訓練去進一步瞭解PFM在根除性攝護腺切除術後對尿失禁的影響。此篇研究透過前瞻性隨機分配的方式將病人分成兩組,一組進行完整的高強度PFM,另一組進行低強度的運動,兩組皆在手術前五週開始進行訓練,並在術後持續12週的訓練,並於術前及術後第2, 6, 12週使用問卷及棉墊測試去評估病人的狀況。結果證明在攝護腺根除手術前加強接受骨盆肌底訓練的運動,能夠有效地減少術後引起的尿失禁及生活品質。
abstract

Background: Pelvic floor muscle training (PFM) training for post-prostatectomy incontinence (PPI) is an important rehabilitative approach, but the evidence base is still evolving. We developed a novel PFM training program focussed on activating fast and slow twitch muscle fibres. We hypothesized that this training, which commenced pre-operatively, would improve PFM function and reduce PPI, when compared to a control group.

Methods: This randomized trial allocated 97 men (63 ± 7y, BMI = 25.4, Gleason 7) undergoing radical prostatectomy (RP) to either a control group (n = 47) performing low-volume rehabilitation, or an intervention group (n = 50). Both interventions commenced 5 weeks prior to surgery and continued for 12 weeks post-RP. Participants were assessed pre-operatively and at 2, 6 and 12 weeks post-RP using 24 h pad weights, International Prostate Symptom Score (IPSS), Expanded Prostate Cancer Index Composite for Clinical Practice (EPIC-CP) and real time ultrasound (RTUS) measurements of PFM function.

Results: Following RP, participants in the control group demonstrated a slower return to continence and experienced significantly more leakage (p < 0.05), measured by 24 h pad weight, compared to the intervention group, suggesting an impact of the prehabilitation protocol. PFM function measures were enhanced following RP in the intervention group. Secondary measures (IPSS, EPIC-CP and RTUS PFM function tests) demonstrated improvement across all time points, with the intervention group displaying consistently lower “bothersome” scores.

Conclusions: A pelvic floor muscle exercise program commenced prior to prostate surgery enhanced post-surgical measures of pelvic floor muscle function, reduced PPI and improved QoL outcomes related to incontinence.

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