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| 發表人 | 討論主題 | 發表時間 | 討論數 |
| 王炯珵 | 下泌尿道症狀會受到代謝症候群的影響嗎？ | 2009/1/15 上午 07:10:35 | 0 |
| 原 文 | 題 目 | Are Lower Urinary Tract Symptoms Influenced by Metabolic Syndrome? |
| 作 者 | Temml C, Obermayr R, Marszalek M, Rauchenwald M, Madersbacher S, Ponholzer A. | |
| 出 處 | Urology | |
| 出版日期 | 2008,Dec 30 in Pubmed | |
| 評 論 |
代謝症候群[Metabolic syndrome(MS)]主要包括肚子肥胖、胰島素阻抗、血脂異常和高血壓等五個因子，在過去許多研究顯示MS和心血管疾病及糖尿病的產生有關，也有人發現在MS的病患，攝護腺生長比較快，但是，是否下泌尿道症狀[Lower Urinary Tract Symptom(LUTS)]會受到MS的影響，則有不同的答案。 來自Austria維也納的研究LUTS和MS的關係顯示，在平均46歲2371位的男性和54歲731位的女性中，33.8%的男性有MS，30.2%的女性有MS，有無MS和IPSS分數的高低，沒有關係。 類似的結果，在韓國一項老人的調查中也有發現(Park HK Urology2008) MS和LUTS無關，而這些結果不同於Rohrmann 2005年在Int J Obesity和Parsons 2007年在J Urology的研究，MS和LUTS是相關的。 看來MS和LUTS的關係目前尚未有定論，雖然大部分動物實驗臨床觀察都偏向兩者有相關，但大家平心而論，您們在看門診時，覺得BPH中胖子比較多嗎？似乎，好像不是這樣耶！ |
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| abstract |
OBJECTIVES: To determine the role of the metabolic syndrome (MS) in the genesis of lower urinary tract symptoms (LUTS) in both sexes. The MS and LUTS are highly prevalent disorders, both increasing with increasing age. METHODS: Participants in a health-screening project underwent a detailed health examination, including all factors associated with the MS, and were assessed regarding LUTS. The MS was defined according to the International Diabetes Federation consensus definition of 2005, and LUTS were quantified using the International Prostate Symptom Score (IPSS). RESULTS: A total of 2371 men (mean age 46.1 years) and 731 women (mean age 53.9 years) were analyzed. In the men, moderate-to-severe LUTS (IPSS >7) were present in 13.1%; in the women, the corresponding value was 23.5%. The proportion of the MS diagnosed during the health investigation was 33.8% in the men and 30.2% in the women. On multiple linear regression analysis, the MS was not associated with the IPSS, IPSS obstructive or irritative subscore, or LUTS. The proportion of LUTS and mean IPSS did not significantly differ regarding the presence or absence of the MS in either sex. CONCLUSIONS: According to our results, the MS did not turn out to be significantly and independently involved in the genesis of LUTS in men or women. |
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